Brand Name: Zometa
Strength: 4 mg
Manufactured By: Novartis Pharmaceuticals Ltd.
Zoledronate is in a group of medicines called bisphosphonates (bis FOS fo nayts). This medicine inhibits the release of calcium from bones. It is a supportive care drug in the category of bisphosphonates.
Zoledronate injection is used as a support medication to treat symptoms of cancer such as hypercalcemia (high blood calcium levels) or to decrease complications (such as fractures or pain) produced by bone metastasis (spread of cancer to the bone). It is also used in treatment of Osteoporosis and other bone diseases.
nausea, vomiting, stomach pain, loss of appetite; diarrhea, constipation; bone pain, back pain, muscle or joint pain; swelling in your feet or ankles; weight loss; headache, tiredness, weakness, dizziness; numbness or tingling; cough, trouble breathing; or sleep problems (insomnia).
Call your doctor at once if you have:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Do not use Zoledronate if you are pregnant. It could harm the unborn baby.
Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Some people using medicines similar to Zometa have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums.
Avoid having any type of dental surgery while you are being treated with Zoledronic acid. It may take longer than normal for you to recover.
Zoledronate can harm your kidneys. This effect is increased when you also use other medicines harmful to the kidneys, such as: chemotherapy, antiviral medication, pain or arthritis medicine, injected antibiotics, or medicines to treat a bowel disorder or prevent organ transplant rejection.
This is not a complete list. Ask your health care provider for more information.
Store at 20° to 25°C (68° to 77°F) excursions permitted between 15° to 30°C (59° to 86°F)
While using this medication, you should not be treated with other bisphosphonates, including other brands of zoledronic acid used to prevent or treat bone loss (osteoporosis).
Also tell your doctor or pharmacist of drugs that may be harmful to your kidneys such as: aminoglycoside antibiotics (e.g., gentamicin, tobramycin), amphotericin B, nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen), tacrolimus.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Zoledronate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.