Xgeva Denosumab Injection





Denosumab Xgeva Injection Specification:

Brand Name: Xgeva
Contents: Denosumab Solution
Manufactured by: Amgen
Marketed by: GlaxoSmithKline (GSK)
Strength: 120mg / 1.7mL
Form: Solution for Injection
Packing: Pack of 1 Vial

 

 

 

 Medicine Details  

 

WHAT IS DENOSUMAB 120 MG ?

Denosumab is a monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. This medications is classified as a "bone-modifying agent". Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.

DENOSUMAB USES :

Denosumab Injection is used to prevent bone fractures and other skeletal conditions in people with tumors that have spread to the bone. It is also used to treat giant cell bone tumor in adults and teenagers with fully matured bone structure. It is also used to treat high blood levels of calcium caused by cancer, when other medicines such as pamidronate or zoledronic acid have been used without success.

XGEVA 120 MG COMMON SIDE EFFECTS :

feeling weak or tired; nausea, vomiting, loss of appetite; diarrhea, constipation; headache, back pain; or pain or swelling in your arms or legs.

Call your doctor at once if you have:

  • new or unusual pain in your thigh, hip, or groin; fast or slow heart rate, trouble breathing;
  • low red blood cells (anemia)--pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
  • low levels of calcium in your blood (hypocalcemia)--numbness or tingly feeling around your mouth or in your fingers or toes, muscle tightness or contraction, overactive reflexes.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

MEDICINE SAFETY INFORMATION :

Before using Denosumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as latex), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood calcium levels (hypocalcemia), thyroid/parathyroid problems/surgery, stomach/intestinal problems (such as malabsorption, surgery), kidney problems, recent or planned dental surgery/tooth removal.

Some people using Xgeva may have serious jawbone problems. Your doctor should check your mouth before you start this medication. Tell your dentist that you are using this medication before you have any dental work done. To help prevent jawbone problems, have regular dental exams and learn how to keep your teeth and gums healthy. If you have jaw pain, tell your doctor and dentist right away.

This medication must not be used during pregnancy. It may harm an unborn baby. Discuss the use of reliable forms of birth control with your doctor. If you become pregnant or think you may be pregnant, tell your doctor right away.

It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.

This is not a complete list. Ask your health care provider for more information.

STORAGE AND HANDLING OF XGEVA GLAXOSMITHKLINE DENOSUMAB :

Store in original carton at 2°C to 8°C (36°F to 46°F). Do not freeze. Prior to use, bring to room temperature of 25°C (77°F) in original container (usually takes 15 to 30 minutes); do not use any other methods for warming. Use within 14 days once at room temperature. Protect from direct heat and light; do not expose to temperatures >25°C (77°F). Avoid vigorous shaking.

DRUG INTERACTIONS :

Drug interactions may change how your medications work or increase your risk for serious side effects. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

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