Opdivo Nivolumab Injection

Opdivo Nivolumab Injection Specification:

Brand Name: Opdivo Injection
Contents: Nivolumab
Manufactured by: Bristol-Myers Squibb
Strength: 100mg/10ml and 40mg/4ml
Form: Injection
Packing: Pack of 1 Vial




 Medicines Details  



Nivolumab belongs to a class of drugs known as monoclonal antibodies. It is a cancer medicine that works with your immune system to interfere with the growth and spread of cancer cells in the body.


  • Nivolumab is used to treat a certain type of melanoma (skin cancer) that cannot be treated with surgery, or that has spread to other parts of the body.
  • It is also used to treat a certain type of non-small cell lung cancer. It may increase the chance of a longer survival time in people with this type of lung cancer.
  • It is used for melanoma or lung cancer only if your tumor has a specific genetic marker that your doctor will test for.
  • This medicine is also used to treat advanced kidney cancer that has not responded to other cancer medicines, or Hodgkin lymphoma that has relapsed or progressed after stem cell transplant and treatment with brentixumab vedotin (Adcetris).


nausea, vomiting, loss of appetite, diarrhea, constipation; feeling tired or short of breath; fever, body aches; cough, runny or stuffy nose; skin rash, itching; or headache.

Call your doctor at once if you have:

  • severe or ongoing diarrhea, severe stomach pain, bloody or tarry stools;
  • new or worsening skin rash;
  • sores or ulcers in your mouth, nose, rectum, or genitals;
  • severe muscle weakness, ongoing pain in your muscles or joints;
  • lung problems - new or worsening cough, sudden chest pain or discomfort, wheezing, feeling short of breath;
  • symptoms of brain swelling - confusion, headache, memory problems, hallucinations, neck stiffness, drowsiness, seizure (convulsions);
  • kidney problems - little or no urinating; blood in your urine; swelling in your feet or ankles;
  • liver problems - nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • signs of a hormonal disorder - frequent or unusual headaches, vision problems, feeling light-headed or very tired, rapid heartbeats, mood or behavior changes, hoarse or deepened voice, increased hunger or thirst, increased urination, constipation, hair loss, sweating, feeling cold, weight gain, or weight loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.


  • Severe and sometimes fatal lung problems have happened with Nivolumab. Call your doctor right away if you have any symptoms of lung or breathing problems (eg, chest pain, new or worsening cough, shortness of breath, trouble breathing).
  • It is common to have diarrhea with Nivolumab. However, a severe bowel problem (colitis) with diarrhea has happened with this medicine. This may lead to tears or holes in the bowels. Call your doctor right away if you have bloody stools; dark, tarry, or sticky stools; diarrhea; or severe stomach pain.
  • Lab tests may be performed while you use Opdivo. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: Opdivo may cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor right away. It is not known if this medicine is found in breast milk. Do not breast-feed while taking it.

This is not a complete list. Ask your health care provider for more information.


Store intact vials at 2°C to 8°C (36°F to 46°F); do not freeze. Protect from light. Do not shake.


Drug interactions may change how your medications work or increase your risk for serious side effects. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

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