Brand Name: Pemnat
Strength: 500 mg
Manufacturer: Natco Pharma Ltd
Pemetrexed is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. It is classified as an "antimetabolite". Premetrexed belongs to the class of chemotherapy drugs called antimetabolites. Antimetabolites are very similar to normal substances within the cell. When the cells incorporate these substances into the cellular metabolism, they are unable to divide. Antimetabolites are cell-cycle specific. They attack cells at very specific phases in the cycle.
Pemetrexed is used in the treatment of malignant mesothelioma and Locally advanced or metastatic nonsquamous nonsmall cell lung cancer.
tired feeling, loss of appetite, weight loss; upset stomach, nausea, vomiting, diarrhea; mild rash; or hair loss.
Call your doctor at once if you have:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Before using Pemetrexed, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe kidney disease.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: decreased bone marrow function/blood cell disorders (e.g., anemia, leukopenia, thrombocytopenia), kidney problems, liver problems.
Do not have immunizations/vaccinations without the consent of your doctor, and avoid contact with people who have recently received oral polio vaccine.
This medication is not recommended for use during pregnancy. It may harm an unborn baby. It is important that men and women using this medication use of reliable forms of birth control (such as condoms, birth control pills) while using this medication and for some period afterwards.
It is not known whether this drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
This is not a complete list. Ask your health care provider for more information.
Store intact vials at room temperature of 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Reconstituted solution in NS and infusion solutions (in D5W or NS) are stable for 24 hours when refrigerated at 2°C to 8°C (36°F to 46°F). Concentrations at 25 mg/mL are stable in polypropylene syringes for 2 days at room temperature (23°C)
Pemnat can harm your kidneys. This effect is increased when you also use certain other medicines, including: antivirals, chemotherapy, injected antibiotics, medicine for bowel disorders, medicine to prevent organ transplant rejection, injectable osteoporosis medication, and some pain or arthritis medicines (including aspirin, Tylenol, Advil, and Aleve).
This document does not contain all possible interactions. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.